A probiotic is a non-pathogenic organism which has a beneficial effect on the health of the host. It may achieve this effect by crowding out other, non-beneficial oiganisms; by producing substances which are toxic to nonbeneficial organisms; and/or by stimulating the host immune system through interaction with Peyer's patches. In order to act as an ideal probiotic, the organism must be able to survive the harsh conditions that exist in the human gut, to establish itself, and to grow. Lactobacillus fermentum KLD (PCC") has demonstrated this ability through tests both in vitro (in our labs) and in vivo (in humans). In vitro, the L fermentum KLD (PCC) has been tested for its ability to survive when exposed to: "pH 1 "pepsin "pH 8 "trypsin, chymotrypsin " bile acids " inoculation into a continuous culture fermenter containing human gut bacteria In vivo, human volunteers were tested to determine if L. fermentum KLD (PCC") could survive and multiply in the variable conditions of the human intestinal tract. Fecal cultures demonstrated that the organism was indeed present in all for at least 48 hours after initial dosing. In conclusion, L fermentum KID (PCC") has all of the properties required to be classified as the ideal probiotic. |
